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Choosing the wrong clean room wipes will result in a loss of 230 million yuan? These 3 technical parameters must be mastered.

May 05, 2025 Knowledge Base Wipestar

In industrial scenarios such as electronic manufacturing, pharmaceutical production and precision instrument assembly, workshop cleanliness control is the core element of product quality assurance. As a key consumable in the clean room cleaning system, the selection and application of professional-grade wipes directly determine the pollutant control efficiency. According to statistics, the global loss of equipment failures caused by improper cleaning tools exceeds US$230 million every year, which highlights the importance of scientifically choosing clean room wipes.

Analysis of the characteristics of professional cleaning tools

Cleanroom-Wipes

Limitations of regular cleaning tools: Why can’t ordinary rags meet clean room needs?  Ordinary textiles have significant defects at the microscopic level: cotton materials release 500-800 fiber debris per square centimeter on average, and chemical fiber products will produce static voltages up to 2000V. Comparative experiments show that after cleaning with a normal rag, the residual particle on the surface of the equipment increased by 47%. The cleaning room special wipe cloth that complies with ISO 14644 standards has achieved breakthroughs through triple technological innovation:

1. Microfiber weaving technology: Use extremely fine fibers with a diameter of 0.1-0.3 denier, and form a million-level adsorption unit through fish bone interlaced braiding

2. Electrostatic neutralization process: After carbon fiber conduction treatment, the surface resistance is stable in the range of 10^6-10^9Ω, effectively inhibiting particle adsorption

3. Chemical inert structure: Use polyester-polyamide composite material, which can withstand various types of cleaners with pH values of 2-12.

Scientific Selection Guide: Building Workshop Cleaning Matrix

When establishing a grading and selection system, it is recommended to refer to the following parameter matrix: Cleanliness Level Applicable Scenarios Fiber Density (Root/cm²) | Cleaner Compatibility ISO Level 4 Wafer Manufacturing/Optical Coating≥1.2×10^6 Electronic Solvents ISO Level 5  Sterile Preparation Workshop 8×10^5 Deionized Water ISO Level 6 Precision Part Assembly5×10^5 Isopropanol

Taking semiconductor wafer factories as an example, the front-end process must use A-level dust-free cloth. After this material is laser edge-sealed, the length of the edge wool is strictly controlled within 50μm. The pharmaceutical workshop should be equipped with a B-grade antibacterial wipe cloth, and its antibacterial rate must reach 99.99% (ASTM E2149 standard).

Cleaning system optimization practice

Before implementing cleaning operations, it is recommended to build a standardized pretreatment process: 1. Tool activation: Balance the clean room wipe cloth in a temperature of 22±2℃ and humidity of 45% RH for 4 hours 2. Solvent infiltration: Use the "three-zone immersion method" to ensure that the cleaner is evenly distributed and no bubbles are generated 3.

Operation specifications: Follow the principle of one-way wiping, replace the wiping surface every 20cm² area to avoid cross contamination

It is worth noting that when 75% concentration isopropanol is used as a cleaning medium, its volatility rate and decontamination performance reach the optimal balance point.

Six-step operating guide for deep cleaning of clean rooms

1. Before operating the professional cleaning tool configuration list, three types of core tools need to be prepared: anti-static and dust-free gloves (the nitrile material is the best), blunt-head anti-pollution tweezers, and double-layer sealed waste treatment bags. It is recommended to use a clean room wipe cloth that has passed ISO Class 5 certification, which has a microfiber structure that can effectively capture particles above 0.1μm.

2. Detailed explanation of standardized cleaning process 2.1 Key steps of surface pretreatment For the surface of equipment attached to heavy oil stains or metal debris, it is recommended to use a phased treatment: first, use an industrial vacuum cleaner equipped with a HEPA filter to remove large particles (particle size > 5μm), and then use a 0.45MPa compressed air gun for secondary purging. This pretreatment reduces the risk of surface scratches over 90% during subsequent wiping.

2.2 Precise application technology for cleaner spraying special cleaners with neutral pH values evenly on the surface of the cleaning room wipe cloth. It is recommended to use three-point spraying method (1/3 of the center of the cloth and 1/3 of each end). Experimental data show that when each 30cm×30cm wipe cloth carries 8±2ml of solution, it can not only ensure the cleaning effect, but also avoid secondary contamination caused by solution dripping.

2.3 The one-way wipe operation specification adopts the "S" trajectory one-way propulsion, similar to the working principle of the automotive wiper. The wipe surface is replaced every 40cm² cleaning area. This method can reduce particle rebound by 67% by verified by the particle counter. Pay attention to the wiping force to be controlled at 200-300g/cm², which is equivalent to the force imposed by the handheld egg.

2.4 Precision area treatment plan For gap structures below 0.5mm, it is recommended to fold the wipe cloth into 1/16 size (about 5cm×5cm), and clean it with 45° inclination tweezers for fixed point cleaning. According to the medical device industry case, this method can increase the cleaning pass rate of connector interfaces to 99.3%.

2.5 The visual inspection of the dual-track mechanism of quality verification must be carried out at 2000Lux illumination, focusing on observing the residuals of the reflective angle. Instrument verification should comply with the ISO 14644-1 standard, and it is recommended to use a laser particle counter to ensure that the number of particles with a particle size of ≥0.5μm is less than 3520/m³.

2.6 The wipe cloth after use of closed-loop management of pollution control should be put into a double-layer PE sealed bag immediately and marked with the "controlled waste". Research shows that standardized treatment can reduce the number of air colonies in clean rooms by 4 logarithmic units, reaching the GMP A-level regional standard.

3. Typical operational misunderstandings Technical analysis misunderstandings 1: The laboratory comparison of mechanical force substitution chemical action shows that pressure wipe 600g/cm² will increase the fracture rate of microfine fibers by 8 times. The correct way is to keep the wipe cloth in full contact with the surface, and rely on capillary action to achieve stain transfer, similar to the principle of natural diffusion of ink drops on rice paper.

【Professional Guide】Cleaning room cleaning operation specifications and cost optimization strategies

In-depth analysis of common operational misunderstandings Misunderstandings 3: Potential risks of detergent residues A well-known electronics manufacturing company caused batch corrosion of circuit boards due to isopropanol residues, and the direct economic loss reached 580,000 yuan. It is recommended to give priority to detergents with boiling points in the range of 60-80°C, such as GMP certified electronic grade isopropanol, which can volatilize at a 25°C environment of up to 0.35 ml/min·m². The operating specifications require that the standstill time after cleaning must meet the calculated value of T≥ (film thickness × 3)/volatilization rate formula. It is usually recommended to maintain the ventilation waiting period for 3-5 minutes.

Economic Assessment of Cleaning Materials 4.1 Cost-benefit Analysis: The long-term value of professional cleaning materials takes a 100,000-level clean workshop as an example. The comparison data of professional cleaning room wipes and ordinary fiber rags shows that within a three-year cycle, the overall cost per unit area of using ISO Class 5 standard dust-free cloth is reduced by 42%. Comparison of key parameters: • Particle residue: Medical grade dust-free cloth ≤ 0.1μm particles 5 particles/cm² vs 300+ pieces/cm² • Cross-contamination rate: Professional materials can be controlled below 0.02%. Actual cases in semiconductor manufacturing workshops show that after the conversion of double-layer pressed dust-free cloth, the product failure rate dropped from 1.8% to 0.3%, which is equivalent to an annual quality cost reduction of 2.4 million yuan.

The standardized cleaning process for invisible benefits of equipment maintenance can significantly extend the service life of precision equipment. The maintenance records of a biopharmaceutical company's freeze-drying unit show that: • The replacement cycle of high-efficiency filters is extended by 60% • The failure interval between transmission systems is increased to 1,800 hours • The annual maintenance budget is reduced by 28% This is mainly due to the dust removal efficiency of 99.99% of professional dust-free cloth, which is a qualitative improvement in cleanliness compared to the 76% cleanliness of traditional cotton materials.

Technical QAA Selection

The value chain of standardized cleaning is to reconstruct the essence of cleaning operations in a precision manufacturing environment. Just like the gear transmission system of precision instruments, the standardized operation of each cleaning step directly affects the overall performance of the workshop.

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